Emerging technologies in protein and genomic material anaylsis / edited by György Marko-Varga and Peter L. Oroszlan.

Includes bibliographical references and index.

Enabling Bio-analytical Technologies for Protein and Genomic Material Analysis and their Impact on Biology / Gyorgy A. Marko-Varga, Peter Oroszlan -- Industrial impact -- Proteomics--the new frontier after the human genome -- Human proteome initiatives -- Multidimensional liquid chromatography -- Fast and sensitive protein sequencing by mass spectrometry -- Protein chip arrays -- DNA/RNA analysis -- Pharmacogenomics -- Miniaturized, micro-scale systems -- Nano-sciences and nano-scale analytical systems -- DNA Sequencing: From Capillaries to Microchips / Andras Guttman -- The early days of automated DNA sequencing -- The advent of capillary gel electrophoresis -- Towards higher throughput: capillary array electrophoresis -- The promise of miniaturization: microchips -- Dealing with the data: bioinformatics -- Phosphorprotein and Phosphoproteome Analysis by Mass Spectrometry / Mads Gronborg, Ole Norregaard Jensen -- Phosphoprotein analysis: A challenge for mass spectrometry -- Mass spectrometry based phosphatase/kinase assays -- Phosphoprotein and phosphopeptide enrichment strategies -- Chemical derivatization of phosphopeptides and phosphoproteins -- Selective detection and sequencing of phosphopeptides by tandem mass spectrometry -- Liquid chromatography--tandem mass spectrometry (LC-MS/MS) -- Phosphoproteome analysis by mass spectrometry -- Emerging MS methods for phosphoprotein analysis -- Relative quantitation of phosphorylation site occupancy by stable isotope labeling of proteins.