Advances in combination therapy for asthma and COPD / [Book] / [edited by] Jan Lotvall, William Busse.

Includes bibliographical references and index.

Similarities and differences in the pathophysiology of asthma and COPD / Christian Virchow -- Glucocorticoids : pharmacology and mechanisms / Peter Barnes -- Inhaled corticosteroids ? clinical effects in asthma and COPD / Paul O'Byrne -- LABAS : pharmacology, mechanisms and interaction with anti-inflammatory treatments / Gary Anderson -- Long and ultra-long acting beta-2-agonists / Mario Cazzola -- The safety of long-acting beta agonists and the development of combination therapies for asthma and chronic obstructive pulmonary disease / Eugene Bleecker -- Inhaled combination therapy with glucocorticoids and long-acting beta-2-agonists in asthma and COPD, current and future perspectives / Jan Lotvall -- Novel anti-inflammatory treatments for asthma and COPD / Ian Adcock -- Novel biologicals alone and in combination in asthma and allergy / William Busse -- Anti-infective treatments in asthma and COPD / Jonathan D.R. Macintyre & Sebastian L. Johnston -- Long acting muscarinic antagonists in asthma and COPD / Denis O'Donnell -- Phosphodiesterase inhibitors in obstructive lung disease / Jan Lotvall -- Biological therapies in development for COPD / Riccardo Polosa -- Triple therapy?, in the management of chronic obstructive lung disease (COPD). The value of combination treatment with inhaled steroid, long acting anticholinergicbronchodilator and long acting beta 2 agonist bronchodilator in COPD / Ronald Dahl.

Aimed at specialists in respiratory medicine, this new book comprehensively reviews the variety of agents currently available for treatment of asthma, COPD, and other airway diseases and covers practical guidelines as well as challenges and complications in their use. Advances in Combination Therapy for Asthma and COPD is the first book to address the complexity of multi-agent therapy and deal with management issues in an integrated fashion. A review of currently available agents and their applications, as well as new therapies soon to become available are outlined. Advantages of combined therapies and additional considerations that arise from multi-agent programs are highlighted.

All.